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Alpha Lipoic Acid Explored as Anti-aging Compound

September 8th, 2011

Are You Ready?! Researchers announced they have identified the mechanism of action of lipoic acid, a remarkable compound that in animal experiments appears to slow down the process of aging, improve blood flow, enhance immune function and perform many other functions.


Alpha Lipoic Acid is a vitamin-like antioxidant that is produced naturally in the body. As a free radical scavenger, it is unique because it is both fat and water soluble. It is easily absorbed and transported across cell membranes offering protection (against free radicals) both inside and outside the cell. Other antioxidants only provide extra cellular protection.

“The evidence suggests that lipoic acid is actually a low-level stressor that turns on the basic cellular defenses of the body, including some of those that naturally decline with age,” said Tory Hagen, an LPI researcher and associate professor of biochemistry and biophysics at OSU. “In particular, it tends to restore levels of glutathione, a protective antioxidant and detoxification compound, to those of a young animal. It also acts as a strong anti-inflammatory agent, which is relevant to many degenerative diseases.”

“Our studies have shown that mice supplemented with lipoic acid have a cognitive ability, behavior, and genetic expression of almost 100 detoxification and antioxidant genes that are comparable to that of young animals,” Hagen said. “They aren’t just living longer, they are living better — and that’s the goal we’re after.”

What the OSU researchers now believe is that the role of lipoic acid is not so much a direct one to benefit cells, but rather an indirect aid that “kick starts” declining function in cells and helps them recover the functions that came more easily and naturally in young animals.

In various effects, lipoic acid appears to help restore a cellular “signaling” process that tends to break down in older blood vessels. It reduces mitochondrial decay in cells, which is closely linked to the symptoms of aging. With age, Glutathione levels naturally decline, making older animals more susceptible to both free radicals and other environmental toxins – but, lipoic acid can restore Glutathione function to near normal. And the expression and function of other genes seems to come back to life.

“We never really expected such a surprising range of benefits from one compound,” Hagen said. “This is really unprecedented, and we’re pretty excited about it.”

This is exciting news and House of Nutrition has some incredible bargains right now on supplements.  Stop by and check out our low prices on Alpha lipoic Acid supplements:

Jarrow’s Formula – Alpha Lipoic Acid 100mg is very popular.

But these are great too!

Country Life’s – Biochem Lipoic Acid 100mg

Food Science’s – Alpha Lipoic Acid 60Caps

Kal’s – Alpha Lipoic Acid 100mg

Best Health,

-Jeanne Ricks, CHC, AADP

Don’t Blame Genetics!

September 7th, 2011

The one thing I truly loathe hearing is people blaming their past, current or future health problems completely on genetics. It bothers me that people are so easy to put their own personal health out of their own hands. When someone blames their health condition completely on genetics, not only have they attempted to take blame off of their lifestyle, but even more important is that they have taken the healing out of their hands. Well, your genetics are not the end-all-be-all, epi-genetics is a more accurate way of looking at health conditions.

Epigenetics, straight from its Latin derivative is outer-genetics meaning outside sources that impact gene expressions. What this means is that there are non-genetic influences on your DNA, which impacts how it is expressed. So if you tell me that you have high cholesterol because it’s ‘genetic’… Sorry but I just don’t buy it.

Some people will read this and be upset that unless they take control of their lifestyle and their health issue may not resolve. Others may read this and be content that they actually have control over their health condition and then they can resolve their health issue. Which one are you?

I think you can take control of your health condition, modify your lifestyle and eliminate this outer source that is causing chaos upon your body. Essentially, the environment impacts your genes and can cause your body to change and modify itself it order to compensate. Take for example the infamous genetic-blaming disorder hyperlipidemia, also known as high cholesterol and high triglycerides. Many people will see their doctor, and they will be told that they have high cholesterol and if dieting and exercise doesn’t help then it ‘must’ be genetic. However, what if they are just not introducing the right foods, or perhaps they are doing other things like excess alcohol, that could be contributing to their cholesterol issues. Or perhaps they are cholesterol-deprived and their body is trying to compensate with excess cholesterol production. Maybe they are under extreme stress. Each of these aspects are epi, or outside environmental sources.

Nutrigenomics, the study of nutrients on gene expression is a new up and coming science. A book I just read by Naturopath Dr. D’Adamo (of the Blood Type diet) goes very deep into nutrigenomics. It is called The Genotype Diet. This book is way ahead of its time, and I highly suggest you read it. It essentially takes everything I said, but puts it in a book with personalized genetic analysis. Go get it!

-Ralph Esposito

Follow me on twitter @ nutritiondocnyu

Listen to your Body!

August 25th, 2011

I have some homework for you, but don’t worry it won’t require any calculus or Shakespeare literature.  The next time you go food shopping, take a look at the ingredients list on the food you buy. I can almost guarantee that you will find one of these ingredients in your food:

  • Corn
  • Soy
  • Wheat
  • Gluten (common in many wheat/grain products)
  • Dairy
  • Eggs
  • Peanuts

These foods won’t kill you per se, but they are known allergens and depending on the individual they can truly make your body feel sub-par. Many people think an allergen is something you have a physically visible reaction to. For example, many people are allergic to peanuts and have a serious adverse reaction to them. However, this is not always the case with these other allergens.

Why would you want to eliminate these foods, well here are a few reasons.

Tummy Problems:

If you have an gastrointestinal issue that has difficulty going away, like IBS, food intolerances, bloating, gas, indigestion, irregular bowel movements, then eliminating these foods from your diet may, and likely will, relieve or remove these symptoms.

Skin Issues:

If you experience acne or any other skin issues like eczema, dry skin or your skin just isn’t clear, eliminating these foods may give you insight as to the culprit of the problem. By eliminiating these foods, your liver will have the opportunity to actually cleanse the body and not worry about removing these allergenic foods.

Allergies:

If you deal with chronic allergies, not a specific food allergy  (like peanuts), but sinus issues or other allergy symptoms, then perhaps your body is trying to tell you something.

Inflammation:

Chronic inflammation can be very painful and depressing. Dealing with chronic inflammation, such as back pain, nasal issues, or other inflammatory responses can be reduced with eliminating certain foods and introduces others. The body does an excellent job at healing itself, and inflammatory response are the body’s way of trying to clear up and resolve a problem. But how can it do so without the proper nutrients?

I know what you’re thinking. Yes, corn, soy, dairy, eggs, peanuts, soy, wheat and gluten are in a lot of foods, a lot, and yes it is hard to avoid these things. But it is not impossible, I know because I have done this exact program.

As one of my favorite professors, Dr. Sheldon Watts, once said, “Eat as close to the farm as possible.” Although most of us live very farm from farms, we can find foods in the market that are not processed or filled with corn, soy and the such. By eating more fruits and vegetables, and gluten free grains like oatmeal, buckwheat, brown, rice and quinoa, this program is absolutely possible. Add protein like, Purity’s Ultra Protein Vanilla Shake, wild salmon, free-range chicken, bison meat, or lamb.

This may seem difficult, but by eating healthier in just a week you will feel 10 times better than you thought you could.

Side Note:

  • Try to avoid caffeinated drinks like coffee, soda, and black tea. Opt for ginger tea, decaf organic coffee and WATER!
  • If you can try to buy organic or free-range chicken. Bison meat is naturally free-range. Also, wild fish like wild salmon is a much better option, given the additives that are found in farmed fish.

-Ralph

If you like my blogs follow me @nutritiondocnyu on twitter!