Are You Ready?! Researchers announced they have identified the mechanism of action of lipoic acid, a remarkable compound that in animal experiments appears to slow down the process of aging, improve blood flow, enhance immune function and perform many other functions.

Alpha Lipoic Acid is a vitamin-like antioxidant that is produced naturally in the body. As a free radical scavenger, it is unique because it is both fat and water soluble. It is easily absorbed and transported across cell membranes offering protection (against free radicals) both inside and outside the cell. Other antioxidants only provide extra cellular protection.

“The evidence suggests that lipoic acid is actually a low-level stressor that turns on the basic cellular defenses of the body, including some of those that naturally decline with age,” said Tory Hagen, an LPI researcher and associate professor of biochemistry and biophysics at OSU. “In particular, it tends to restore levels of glutathione, a protective antioxidant and detoxification compound, to those of a young animal. It also acts as a strong anti-inflammatory agent, which is relevant to many degenerative diseases.”

“Our studies have shown that mice supplemented with lipoic acid have a cognitive ability, behavior, and genetic expression of almost 100 detoxification and antioxidant genes that are comparable to that of young animals,” Hagen said. “They aren’t just living longer, they are living better — and that’s the goal we’re after.”

What the OSU researchers now believe is that the role of lipoic acid is not so much a direct one to benefit cells, but rather an indirect aid that “kick starts” declining function in cells and helps them recover the functions that came more easily and naturally in young animals.

In various effects, lipoic acid appears to help restore a cellular “signaling” process that tends to break down in older blood vessels. It reduces mitochondrial decay in cells, which is closely linked to the symptoms of aging. With age, Glutathione levels naturally decline, making older animals more susceptible to both free radicals and other environmental toxins – but, lipoic acid can restore Glutathione function to near normal. And the expression and function of other genes seems to come back to life.

“We never really expected such a surprising range of benefits from one compound,” Hagen said. “This is really unprecedented, and we’re pretty excited about it.”

This is exciting news and House of Nutrition has some incredible bargains right now on supplements.  Stop by and check out our low prices on Alpha lipoic Acid supplements:

Jarrow’s Formula – Alpha Lipoic Acid 100mg is very popular.

But these are great too!

Country Life’s – Biochem Lipoic Acid 100mg

Food Science’s – Alpha Lipoic Acid 60Caps

Kal’s – Alpha Lipoic Acid 100mg

Best Health,

-Jeanne Ricks, CHC, AADP

The one thing I truly loathe hearing is people blaming their past, current or future health problems completely on genetics. It bothers me that people are so easy to put their own personal health out of their own hands. When someone blames their health condition completely on genetics, not only have they attempted to take blame off of their lifestyle, but even more important is that they have taken the healing out of their hands. Well, your genetics are not the end-all-be-all, epi-genetics is a more accurate way of looking at health conditions.

Epigenetics, straight from its Latin derivative is outer-genetics meaning outside sources that impact gene expressions. What this means is that there are non-genetic influences on your DNA, which impacts how it is expressed. So if you tell me that you have high cholesterol because it’s ‘genetic’… Sorry but I just don’t buy it.

Some people will read this and be upset that unless they take control of their lifestyle and their health issue may not resolve. Others may read this and be content that they actually have control over their health condition and then they can resolve their health issue. Which one are you?

I think you can take control of your health condition, modify your lifestyle and eliminate this outer source that is causing chaos upon your body. Essentially, the environment impacts your genes and can cause your body to change and modify itself it order to compensate. Take for example the infamous genetic-blaming disorder hyperlipidemia, also known as high cholesterol and high triglycerides. Many people will see their doctor, and they will be told that they have high cholesterol and if dieting and exercise doesn’t help then it ‘must’ be genetic. However, what if they are just not introducing the right foods, or perhaps they are doing other things like excess alcohol, that could be contributing to their cholesterol issues. Or perhaps they are cholesterol-deprived and their body is trying to compensate with excess cholesterol production. Maybe they are under extreme stress. Each of these aspects are epi, or outside environmental sources.

Nutrigenomics, the study of nutrients on gene expression is a new up and coming science. A book I just read by Naturopath Dr. D’Adamo (of the Blood Type diet) goes very deep into nutrigenomics. It is called The Genotype Diet. This book is way ahead of its time, and I highly suggest you read it. It essentially takes everything I said, but puts it in a book with personalized genetic analysis. Go get it!

-Ralph Esposito

Follow me on twitter @ nutritiondocnyu

Straight from the docks – fresh evidence that Fish Oil is absolutely essential to your health – especially for cognitive brain function, as well as aging.

Researchers at Rhode Island Hospital’s Alzheimer’s Disease & Memory Disorders Center have found positive associations between Fish Oil supplements and cognitive functioning as well as differences in brain structure between users and non-users of Fish Oil supplements. The findings suggest possible benefits of Fish Oil supplements on brain health and aging.

       The results were reported at the recent International Conference on Alzheimer’s Disease, in Paris, France that just wrapped-up on July 21^st; and truly provide new hope for anybody concerned about the long-range health of their brain.hmmmm, are you taking Fish Oil?

       The study included 819 individuals, 117 of them reported regular use of Fish Oil supplements before entry and during study follow-up. The researchers compared cognitive functioning and brain degeneration for patients who reported routinely using these supplements to those who were not using Fish Oil supplements.

       Lori Daiello, PharmD, lead researcher, reports that compared to non-users, use of Fish Oil supplements was associated with better cognitive functioning. However, this association was significant only in those individuals who had a normal baseline cognitive function and in individuals who tested negative for a genetic risk factor for Alzheimer’s Disease known as APOE4. This is consistent with previous research.

       The unique finding, however, is that there was a clear association between Fish Oil supplements and brain volume.In other words, Fish Oil use was associated with less brain shrinkage in patients taking these supplements during the study compared to those who didn’t use them.

Hey, but before you click over to House of Nutrition to get your brain healthy product – you should probably ask – How do I chose a Fish Oil supplement? 

Glad you asked!  Here are some easy tips.

• Look for the seal. Companies including USP and NSF analyze supplements for the real vitamin level and for any impurities. The seal on the label tells you an independent company has reviewed the supplement.Also, a reputable company will also ensure that the purity, quality and your safety are guaranteed.
• Look for oil which is molecularly distilled, a process that takes place in a vacuum to avoid oxidation of Fish Oil. This is the only process that successfully removes impurities and contaminants from Fish Oil. This process also produces a more concentrated form of Fish Oil supplement with high potencies of EPA and DHA.
• Look for a product that’s “species specific,” with fish like wild Salmon, Anchovies and Sardines on the label (btw these are the specific varieties which have the highest levels and the best Fish Oil for Omega-3). This is the only way to know where the oil came from. When a supplement label just says “fish oil” or “marine lipids,” they’re hiding something and the product should NOT be considered.
• Look for supplements that have a balanced ratio of all eight Omega-3 fatty acids. Research has proven that all eight members of the Omega-3 family are vitally important to your health. The Omega-3 nutrients need to be complete and balanced, just like they are in nature, in order to be beneficial. Many people have heard of ALA, DHA and EPA – they’re the Omega-3 ‘all-stars’. But DPA, HPA, ETA, ETA and SDA are all just as important. And when the whole Fish Oil family is present, they’re much more powerful than any individual fatty acid.
• Lastly, make sure there are no unlabeled oils or strange ingredients hidden in the product. How? Take a moment to add up the individual Omega-3 fatty acids listed on the label. They should equal the total amount of oil in the product. Otherwise, you’re getting ripped off!

So now that you know what to look for come by and check out some great prices on some really superior Fish Oil products like:

Futurebiotics Omega-3 Fish Oil

Schiff’s Omega-3 Fish Oil Enteric Coated

Natrol’s Omega-3 Fish Oil

Carlson’s Very Finest Norwegian Fish Oil

Best Health,

Jeanne Ricks, CHC, AADP